Unfold

Marvellous Complexity into Tangible Simplicity

with AI

About Us

With over 15 years of experience in the biotech industry, from large companies like Novartis and GSK to startups and venture incubator projects, we bring deep expertise across AI/machine learning, bioinformatics/CompBio, and cloud applications. We offer data analytics services and software solutions to pharmaceutical and biotech companies, helping them to accelerate drug discovery and development, analyze market trends, and identify investment opportunities.

Drug discovery

Life is an extraordinary complexity optimized over billions of years through natural evolution. Diseases however arise from misregulated function and mutated proteins. We leverage AI to design disease-modifying drugs to restore the intricate complexity.

Equity research

Drug development is a costly endeavor that often relies on funding support from public markets. More than 500 (15%) companies in US stock market are in the pharmaceutical and biotech sectors. We conduct public equity research to uncover and track the financial dynamics in the industry.

Cloud applications

Software stands as one of the most successful engineering products. We develop cloud-based software applications to automate and streamline complex workflows, spanning from bioinformatics to AI inference, and deliver high-performance platforms.

Services

We provide expert data science consulting and contracted research services to biotech companies and venture firms. Our expertise spans AI drug discovery, bioinformatics, patent and financial analysis, and software engineering. We help our clients to extract actionable insights from complex datasets, empowering them to make data-driven decisions and maintain a competitive edge.

AI protein design

AI is transforming drug discovery by protein structure modeling and sequence language models. We apply state-of-the-art models to tackle diverse challenges in protein design, enabling accelerated and innovative therapeutic development.

  • Structual modeling and epitope prediction with AlphaFold3/Boltz-1/Chai-1 models.
  • Interface engineering and affinity maturation with protein language models.
  • Physics-based molecular dynamics simulations to calculate mutation-associated ΔΔG.

Patent and FTO survey

The patent literature represents a 30-year record of engineering efforts to create function-enhanced protein variants. This wealth of knowledge provides valuable insights to guide rational protein design. We leverage AI models to optimize therapeutic proteins, generating freedom-to-operate (FTO) analyses for patented molecules and working toward novel and patentable molecules.

  • USPTO and WIPO sequence list serach and anlyses.
  • Protein language modeling on patented protein variants
  • Patent digestion with domain-specific LLM.

Public equity research

Drug development often takes a decade from initial research through clinical trials to commercialization. Every stage of this process is deeply supported and influenced by capital investments. We offer analyses of public biotech companies, examining their pipelines, clinical trials, corporate presentations, financial fundmentals and institutional holdings.

  • SEC filings
  • Corporate website and presentations.
  • Clinical trial notification.

We believe this integrative approach provides a holistic view of the industry's technology and financial dynamics, offering deeper insights into the driving forces in the biotecch market.

Cloud application

We simplify and automate complex workflows by analyzing your processes, identifying bottleneck and creating optimized solutions. We design and implement streamlined pipelines as scalable cloud applications on AWS cloud.

  • Custmized cloud application built on your cloud account.
  • Serverless architecture with cost-effective maintenance.
  • Bioinformatics/CompBio pipelines integrated NGS sequence core.

We aim to ensure enhanced reliability, faster execution and reduced operational costs, empowering your organization to focus on innovation and growth.

Applications

Xunfold AIDD

Cloud-based application that enables AI drug discovery without coding.

  • State-of-the-art AI models, covering folding, protein language models and more.
  • Patent sequence search and FTO survey.
  • In silico envolution.
  • MD simulation.
Get Started
Xunfold Fin

Application for equity research through automated integration of public data.

  • Stock price of trading tickers.
  • SEC filings analysis, including company fundamentals, institutional holdings, and more.
  • Integrative data analysis and company screening to identify key trends and opportunities.
Get Started

We provide free access to apps designed for general-purpose tasks. For more specialized or complex challenges, don't hesitate to get in touch. We're excited to collaborate with you and provide tailored solutions through our consulting services.